Background: Despite all efforts to establish the pathogenesis of malaria, it is far from being understood, and resistance to existing drugs remain a problem in several strains of Plasmodium. Different complications arise during malaria infection, and among these is the alteration...
Open access
Research Article10.9734/JALSI/2018/40708
Aim: In the present study, the alkaloid, flavonoid and saponin-rich extracts of the leaves and seeds of Moringa oleifera were partially-purified and the ACE inhibitory activities and patterns of inhibition determined. Methodology: Alkaloids, flavonoids and saponins were extracted...
Open access
Research Article10.9734/JABB/2016/21974
Background: Alteration of redox status is a fundamental process in the manifestation of many diseases including malaria. Studies have demonstrated that peptides of the renin-angiotensin-aldosterone system (RAAS), such as Angiotensin Converting Enzyme and Angiotensin II, play a si...
Open access
Research Article10.9734/AJB2T/2018/41424
Aim: This study was carried out to investigate the effect of captopril on serum liver enzymes (AST, ALT, and ALP), total serum protein and kidney function parameters such as electrolytes (HCO3-, Cl-, Na+, and K+), urea and creatinine in Plasmodium berghei-infected mice. Methodol...
Open access
Research Article10.9734/JAMPS/2018/40599