Prevalence and Pattern of KRAS and NRAS Mutations in Colorectal Cancer: A Libyan Retrospective Study
Khaled S. Ben Salah, Fatma M. Emaetig, Abdalla O. Jebriel, Nada A. Oshah, Mohamed A. Elfagieh & Ebrahim H. El Mahjoubi · International Research Journal of Oncology · 2021
About 53% of colorectal cancer (CRC) patients were reported to have the Kirsten rat sarcoma viral oncogene homolog (KRAS) gene mutations. These mutations in the KRAS gene are able to render the targeted therapy agents such as monoclonal antibodies cetuximab and panitumumab ineffe...
Open access
Research Article