Computational Exploration of Potential Polo-Like Kinase 1 Inhibitors as New Chemotherapeutic Agents
Mubarak A. Alamri & Ahmed D. Alafnan · Journal of Pharmaceutical Research International · 2020
Background and Objective: Polo like kinase-1 (PLK-1) enzyme belongs to serine/threonine protein kinase family that is regarded as a principle mitotic controller of G2-M phase transition. The antimitotic therapies are a cornerstone for the treatment of metastatic as well as benign...
Open access
Research Article
10.9734/jpri/2020/v32i2930880