Formulation, in vitro and Bioavailability Assessments of Ranitidine Rectal Suppositories
Khaled Shalaby, Ahmed M. Samy, Alaa Kassem, Mohamed F. Ibrahim, Nabil K. Alruwaili, Hazim M. Ali & Mohammed Elmowafy · Journal of Pharmaceutical Research International · 2019
The objective of the current work was to develop and evaluate suppository dosage form in order to improve ranitidine bioavailability as a substitute to the oral administration. Suppocire (different grades), Witepsol W25 and polyethylene glycol (PEG) were used as suppository bases...