Antioxidant Traits and Protective Impact of Vorinostat against Cisplatin Induced Hepatoxicity in Rats
Hala Salah Abdel Kawy Eweis, Omnyah Mohammad Omar Bashraf, Ahmed Shaker Ali & Soad Shaker Ali · Journal of Pharmaceutical Research International · 2020
Background and Aim: Cisplatin "cis diamminedichloroplatinum [II] (CDDP) is the most widely used drug in cancer chemotherapy and hepatotoxicity is one of its major side effects. Vorinostat (VST) has been recognized to have an antioxidant and anti-inflammatory effect in low doses....