(1H-Pyrrolo [2,3-b]pyridine)7-Azaindole Derivatives and Their Antiurease, Phosphodiesterase and β-glucuronidase Activity
Zafar S. Saify, Nighat Sultana, Ajmal Khan & Shazia Haider · International Journal of Biochemistry Research & Review · 2015
A variety of 7-azaindole analogs 1-14 with variable substituents on phenyl ring of phenacyl moiety were synthesized and evaluate for their urease, phosphodiesterase and b-glucuronidase Inhibitory potential. Compound 9 (IC50 = 2.19±0.37µM) showed potent urease inhibitory potential...
Open access
Research Article
10.9734/IJBCRR/2015/10575