Aleksandr P. Yengoyan

Synthesis and Biological Activity of Novel 5-(Alkylthio)-1,3,4-thiadiazol-2(3H)-thione Derivatives

Elen N. Hambardzumyan, Asya S. Vorskanyan, Ani A. Grigoryan & Aleksandr P. Yengoyan · Chemical Science International Journal · 2016

Some nonfused biheterocyclic system derivatives containing a combination of 1,3,4-thiadiazole and pharmacophores such as 1,3,4-oxadiazole and/or pyrazoles in the same molecule were obtained based on 2-((5-(alkylthio)-1,3,4-thiadiazol-2-yl)thio)acetohydrazide. The synthesized comp...

Open access Research Article 10.9734/ACSJ/2016/26657

Synthesis of Novel Derivatives on the Basis of 4-Hydrazinyl-6-methyl-2-(alkylthio)pyrimidines and Their Preliminary Biological Evaluation

Vergush A. Pivazyan, Emma A. Ghazaryan, Roza S. Shainova, Rafael A. Tavalyan, Armen G. Ayvazyan & Aleksandr P. Yengoyan · Chemical Science International Journal · 2016

By functionalization of 4-hydrazinyl-6-methyl-2-(alkylthio)pyrimidines the corresponding acetohydrazides, N-phenylhydrazine-1-carboxamides(thioamides) were obtained. The heterocyclization of the same hydrazides lead to nonfused pyrazolyl-pyrimidines and pyridazinyl-pyrimidines an...

Open access Research Article 10.9734/ACSJ/2016/28201