Is Defibrotide Prophylaxis Effective on Graft Versus Host Disease in Patients with Allogeneic Stem Cell Transplantation?
Irfan Yavasoglu, Atakan Turgutkaya, Hilal Eroğlu Küçükdiler, Gürhan Kadıköylü, Gökhan Sargın & Ali Zahit Bolaman · International Blood Research & Reviews · 2022
Introduction: Sinusoidal obstruction syndrome (SOS) is one of the complications of allogeneic stem cell transplantation (allo-SCT). Defibrotide (DF) is used effectively in SOS prophylaxis and treatment. Graft versus host disease (GVHD) is a significant cause of morbidity and mort...