High-risk Shadows in a Favorable-risk Disease: The Indian Genomic Landscape of CBF-AML
Bhargava Rahul, Nathany Shrinidhi, Surange Devyani, Swaminathan Anusha, Dua Vikas, Bhurani Dinesh, K Nath Swarsat, Makda Moin, Panda Rastogi Neha, Arora Sunisha, Chakraborty Sohini, Garg Paritosh, Verma Haristuti, Shrivastava Harshu, Gupta Aastha, Raizada Niti, Ahmed Rayaz, Singh Reema, Singh Aakanksha & Pachauri Priyanshi · Asian Hematology Research Journal · 2026
Background: Core-binding factor AML (CBF-AML), defined by RUNX1::RUNX1T1 and CBFB::MYH11 fusions, is conventionally classified as favorable-risk. Genomic data from low- and middle-income countries such as India remain limited. Aims: This study aimed to characterise the co-mutatio...