Atohoun G. Sylvain

DFT Study of the Coordination of N-monochlorosubstituted Derivatives of the N-deprotonated Tautomer of the Biguanide

Aïdote François, Kuevi Urbain Amah, Kpotin Assongba Gaston & Atohoun G. Sylvain · International Research Journal of Pure and Applied Chemistry · 2020

Biguanides [HN=C(NR1R2)-NH-C(NR3R4)=NH] constitute an important family of molecules used as drugs in the treatment of diabetes. When R1=R2=R3=R4=H the molecule is named simply “biguanide”. The five nitrogen atoms are potential coordination sites. Several experimental works publis...