Ayad K. Ali

Signal Detection and Clarification of Peripheral Neuropathy and Guillain-Barré Syndrome Associated with Exposure to Systemic Fluoroquinolones

Ayad K. Ali · Journal of Pharmaceutical Research International · 2013

Aims: Peripheral neuropathy (PN) is an identified risk of systemic antibacterial therapy with fluoroquinolones. The risk and its severity, including the development of Guillain-Barré syndrome (GBS) between individual agents is uncertain. This study examines the association betwee...

Open access Research Article 10.9734/BJPR/2014/6954

Pharmacovigilance Analysis of Adverse Psychiatric Events and Suicidality Reported for Roflumilast, an Add-On COPD Therapy

Ayad K. Ali · Journal of Pharmaceutical Research International · 2013

Aims: Roflumilast is a phosphodiesterase-4-inhibitor used as add-on therapy to long-acting bronchodilators in chronic obstructive pulmonary disease. Although roflumilast is well tolerated, there have been concerns regarding psychiatric problems, including suicide tendencies. This...

Open access Research Article 10.9734/BJPR/2013/5633

Methodological Challenges in Observational Research: A Pharmacoepidemiological Perspective

Ayad K. Ali · Journal of Pharmaceutical Research International · 2013

Pharmacoepidemiology is the science of studying the effects of utilizing pharmaceutical and biological products in the population, and in most cases this science is conducted in observational epidemiological designs, including retrospective database analysis. Observational pharma...

Open access Research Article 10.9734/BJPR/2013/2838