C. A. Obafemi

Synthesis of Sulfanoquinoxaline-2,3-Dione Hydrazones Derivatives as a Selective Inhibitor for Acetylcholinesterase and Butyryl Cholinesterase

F. O. Taiwo, C. A. Obafemi, E. M. Obuotor & I. J. Olawuni · Journal of Applied Life Sciences International · 2021

Some Sulfanoquinoxaline-2,3-diones hydrazone derivatives (1-8) were synthesized from the reactions of 2,3-dioxoquinoxaline-6-sulfonohydrazine with seven substituted benzaldehydes and acetophenone. All the synthesized compounds were biologically evaluated against cholinesterase’s...

Open access Research Article 10.9734/jalsi/2021/v24i830252

Design, Synthesis and Antibacterial Activity of some 3,6-Dimethlyquinoxaline-2-Hydrazone Derivatives

F. O. Taiwo, C. A. Obafemi, D. A. Akinpelu & T. O. Iyiola · Journal of Applied Life Sciences International · 2021

Aims: This aims of this study was to continue the effort to synthesis new quinoxaline-based heterocycles and study its antibacterial properties. Objective: This study was designed to reacts 3,6-dimethylquinoxaline-2-hydrazine with some substituted aromatic ketones and study their...

Open access Research Article 10.9734/jalsi/2021/v24i630244

Synthesis of (Z)-2-((2-(Benzylideneamino)ethyl)Amino)-3-Methylquinoxaline-6-Sulfonyl Azide Derivatives and Their Acetylcholinesterase and Butyryl Cholinesterase Inhibitory Activities

Taiwo, F. O, O. B. Omoyeni, I. J. Olawuni, E. G. Fakola & C. A. Obafemi · Journal of Applied Life Sciences International · 2026

Aims: This study synthesized  a series of (Z)-2-((2-(benzylideneamino)ethyl)amino)-3-methylquinoxaline-6-sulfonyl azide derivatives and evaluated their inhibitory activities against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). Methods: The derivatives were prepar...

Open access Research Article 10.9734/jalsi/2026/v29i5800