High Membrane Cholesterol in CLL B-Cells and Differential Expression of Cholesterol Synthesis Genes in IG GENE-Unmutated vs Mutated Cells
Cécile Tomowiak, Anne Kennel, Hélène Gary-Gouy, Nader Hadife, Pierre Feugier, Torsten Haferlach, Marie C Béné & Ali Dalloul · Journal of Advances in Medicine and Medical Research · 2012
Objectives: Chronic lymphocytic leukaemia (CLL) is associated with abnormalities of the B-Cell Receptor (BCR) signalling, including low responsiveness to antigenic stimulation and constitutive phosphorylation of several components of the signalling pathway. In B-cells, BCR-mediat...
Open access
Research Article
10.9734/BJMMR/2012/944