Celso Eduardo Olivier, Daiana Guedes Pinto, Ana Paula Monezzi Teixeira, Cibele Silva Miguel, Nicole Sartoreto Rocha, Alessandra Vieira de Oliveira, Luciana Sacilotto Carvalho, Raquel Acácia Pereira Gonçalves Santos, Jhéssica Letícia Santos Santana & Regiane Patussi Santos Lima·Asian Journal of Immunology·2026
Background: Clinical hypersensitivity to pollen and latex allergens has been studied and linked to hypersensitivity to a variety of fruits and vegetables, making this a complex field of study for respiratory, occupational, and food-allergic patients. Aim: To evaluate the potentia...
Open access
Research Article10.9734/aji/2026/v9i1199
Celso Eduardo Olivier, Daiana Guedes Pinto, Ana Paula Monezzi Teixeira, Cibele Silva Miguel, Alessandra Vieira de Oliveira, Luciana Sacilotto Carvalho, Nicole Sartoreto Rocha & Raquel Acácia Pereira Gonçalves Santos·Asian Journal of Immunology·2026
Background: Chromium compounds can elicit hypersensitivity reactions. No standardised laboratory assay is available to quantify the relative contributions of humoral and cellular mechanisms within an individual patient’s phenotype, apart from in vivo provocation testing. Aim: To...
Open access
Research Article10.9734/aji/2026/v9i1194
Background: Non-IgE-mediated food protein-induced gastrointestinal allergies (FPI-GIAs) are poorly understood, although IgE-mediated hypersensitivities have been extensively described. Patients with poultry meat allergy may present several phenotypes regarding clinical presentati...
Open access
Research Article10.9734/aji/2025/v8i1172
Background: The cat-pork syndrome and the cross-reactivity between cat dander and dog dander are particular situations associated with the allergic multimorbidity phenotypes. The perception of this cross-reactivity must benefit the allergist dealing with these conditions. Aim: To...
Open access
Research Article10.9734/aji/2025/v8i1168
Background: Panallergens, such as tropomyosin, produce cross-reactivity between indoor allergens and food allergens, including the house dust mite Blomia tropicalis and the Brazilian pink shrimp Farfantepenaeus brasiliensis, and are responsible for the clinical symptoms present i...
Open access
Research Article10.9734/aji/2025/v8i1169
Background: Several publications report that formaldehyde is responsible for hypersensitivity reactions in patients with contact dermatitis, as diagnosed by "in vivo" provocation tests. There is no standardized lab exam that can endotype the mechanisms responsible for these pheno...
Open access
Research Article10.9734/aji/2025/v8i1161
Background: Cocoa is one of the foods more consistently associated with high nickel content, a metal that functions as a hapten responsible for various non–IgE-mediated symptomatic hypersensitivities. Aim: The present study is a proof-of-concept that hypothesizes that LAIT and th...
Open access
Research Article10.9734/aji/2025/v8i1158
Celso Eduardo Olivier, Daiana Guedes Pinto, Ana Paula Monezzi Teixeira, Cibele Silva Miguel, Raquel Acácia Pereira Gonçalves Santos, Nicole Sartoreto da Rocha, Jhéssica Letícia Santos Santana & Regiane Patussi Santos Lima·Asian Journal of Immunology·2025
Background: Allergies to citrus fruits are often associated with pollinosis due to cross-reactivity among pollen and food allergens (fruit-pollen syndrome) displayed in patients with several conditions, such as allergic rhinoconjunctivitis. Aim: To evaluate the potential of the T...
Open access
Research Article10.9734/aji/2025/v8i1156
Celso Eduardo Olivier, Daiana Guedes Pinto, Ana Paula Monezzi Teixeira, Cibele Silva Miguel, Raquel Acácia Pereira Gonçalves Santos, Jhéssica Letícia Santos Santana & Regiane Patussi Santos Lima·Asian Journal of Immunology·2024
Background: Several publications report lanolin as responsible for hypersensitivity reactions in patients with atopic dermatitis and/or contact dermatitis, as diagnosed by in vivo provocation tests. There is no standardized lab exam that can endotype the mechanisms responsible fo...
Open access
Research Article10.9734/aji/2024/v7i1154
Celso Eduardo Olivier, Daiana Guedes Pinto, Ana Paula Monezzi Teixeira, Cibele Silva Miguel, Raquel Acácia Pereira Gonçalves Santos, Jhéssica Letícia Santos Santana & Regiane Patussi Santos Lima·Asian Journal of Immunology·2024
Background: Hypersensitivity to chicken eggs is the second most common food allergy, presenting IgE-mediated and non-IgE-mediated hypersensitivity mechanisms. While IgE-mediated hypersensitivity is easily detected, non-IgE-mediated endotypes present challenging obstacles to diagn...
Open access
Research Article10.9734/aji/2024/v7i1150
Celso Eduardo Olivier, Daiana Guedes Pinto, Ana Paula Monezzi Teixeira, Cibele Silva Miguel, Raquel Acácia Pereira Gonçalves Santos, Jhéssica Letícia Santos Santana & Regiane Patussi Santos Lima·Asian Journal of Immunology·2024
Background: Several publications report that tartrazine is responsible for IgE-mediated and non–IgE-mediated hypersensitivity reactions. There is no standardized lab exam to endotype non–IgE-mediated immunoreactivity against tartrazine besides in vivo provocation tests. Aim: To e...
Open access
Research Article10.9734/aji/2024/v7i1146
Celso Eduardo Olivier, Daiana Guedes Pinto, Ana Paula Monezzi Teixeira, Cibele Silva Miguel, Raquel Acácia Pereira Gonçalves Santos, Jhéssica Letícia Santos Santana & Regiane Patussi Santos Lima·Asian Journal of Immunology·2024
Background: Spices from the Allium genus season food worldwide, and their widespread use may produce allergic reactions by contact or ingestion. However, the Non–IgE-mediated immunoreactivity against these allergens has not yet been adequately investigated. Aim: To evaluate the p...
Open access
Research Article10.9734/aji/2024/v7i1143
Celso Eduardo Olivier, Daiana Guedes Pinto, Ana Paula Monezzi Teixeira, Jhéssica Letícia Santos Santana, Raquel Acácia Pereira Gonçalves Santos & Regiane Patussi Santos Lima·Asian Journal of Immunology·2024
Background: Several publications report that aluminum is responsible for hypersensitivity reactions. There is no standardized lab exam that can endotype (determine the pathophysiology responsible for the phenotype) hypersensitivity to aluminum. Aim: To evaluate the potential of t...
Open access
Research Article10.9734/aji/2024/v7i1139
Celso Eduardo Olivier, Daiana Guedes Pinto, Ana Paula Monezzi Teixeira, Jhéssica Letícia Santos Santana, Raquel Acácia Pereira Gonçalves Santos & Regiane Patussi Santos Lima·Asian Journal of Immunology·2024
Background: Several publications report polyethylene glycols (PEGs) and PEGylated therapeutics as responsible for non–IgE-mediated allergic reactions. There is no standardized lab exam that can endotype (quantify the participation of these mechanisms inside each patient’s pattern...
Open access
Research Article10.9734/aji/2024/v7i1135
Celso Eduardo Olivier, Daiana Guedes Pinto, Ana Paula Monezzi Teixeira, Jhéssica Letícia Santos Santana, Raquel Acácia Pereira Gonçalves Santos, Regiane Patussi Santos Lima & Everton Salgado Monteiro·Asian Journal of Immunology·2024
Background: Several publications report Dermatophagoides farinae allergens as responsible for several types of non–IgE-mediated allergic reactions. There is no standardized lab exam to endotype (quantify the participation of these mechanisms) in the context of allergic disease pa...
Open access
Research Article10.9734/aji/2024/v7i1134
Celso Eduardo Olivier, Daiana Guedes Pinto, Ana Paula Monezzi Teixeira, Jhéssica Letícia Santos Santana, Raquel Acácia Pereira Gonçalves Santos & Regiane Patussi Santos Lima·Asian Journal of Immunology·2024
Background: Several publications report benzoic acid as responsible for non–IgE-mediated allergic reactions. No standardized lab exam identifies these reactions besides in vivo provocation tests. Aim: To evaluate the potential of the Leukocyte Adherence Inhibition Test (LAIT) to...
Open access
Research Article10.9734/aji/2024/v7i1130
Celso Eduardo Olivier, Daiana Guedes Pinto, Ana Paula Monezzi Teixeira, Jhéssica Letícia Santos Santana, Raquel Acácia Pereira Gonçalves Santos & Regiane Patussi Santos Lima·Asian Journal of Immunology·2024
Aim: To evaluate the potential of the Leukocyte Adherence Inhibition Test (LAIT) to evaluate immunoreactivity against peanut proteins in patients with a clinical diagnosis of non–IgE-mediated Atopic Dermatitis (AD). Study Design: We retrospectively examined the medical charts of...
Open access
Research Article10.9734/aji/2024/v7i1129
Celso Eduardo Olivier, Daiana Guedes Pinto, Ana Paula Monezzi Teixeira, Jhéssica Letícia Santos Santana, Raquel Acácia Pereira Gonçalves Santos, Regiane Patussi Santos Lima & Everton Salgado Monteiro·Asian Journal of Immunology·2024
Aims: To evaluate the potential of the Leukocyte Adherence Inhibition Test (LAIT) to discriminate non–IgE-mediated immunoreactivity against Aspergillus fumigatus in patients with non–IgE-mediated Allergic Rhinitis and/or Asthma. Study Design: We retrospectively examined the medic...
Open access
Research Article10.9734/aji/2024/v7i1125
Celso Eduardo Olivier, Daiana Guedes Pinto, Ana Paula Monezzi Teixeira, Jhéssica Letícia Santos Santana, Raquel Acácia Pereira Gonçalves Santos & Regiane Patussi Santos Lima·Asian Journal of Immunology·2023
Aims: The study aims to evaluate the potential of the Leukocyte Adherence Inhibition Test (LAIT) to discriminate non–IgE-mediated immunoreactivity against Staphylococcus aureus in patients with Intrinsic Atopic Dermatitis (IAD). Study Design: We retrospectively examined the medic...
Celso Eduardo Olivier, Daiana Guedes Pinto, Ana Paula Monezzi Teixeira, Jhéssica Letícia Santos Santana, Raquel Acácia Pereira Gonçalves Santos, Regiane Patussi Santos Lima & Everton Salgado Monteiro·Asian Journal of Immunology·2023
Aims: To evaluate the potential of the Leukocyte Adherence Inhibition Test (LAIT) to discriminate Non–IgE-mediated immunoreactivity against Candida albicans in Atopic Dermatitis () patients with clinical suspicion of hypersensitivity reactions to fungal allergens. Study Design: W...
Celso Eduardo Olivier, Daiana Guedes Pinto, Ana Paula Monezzi Teixeira, Jhéssica Letícia Santos Santana, Raquel Acácia Pereira Gonçalves Santos, Regiane Patussi Santos Lima & Everton Salgado Monteiro·Asian Journal of Immunology·2023
Aims: To evaluate the potential of the Leukocyte Adherence Inhibition Test (LAIT) to discriminate innate immunoreactivity against Alternaria alternata in patients with clinical suspicion of allergic reaction to fungal allergens. Study Design: We retrospectively examined the medic...
Celso Eduardo Olivier, Daiana Guedes Pinto, Ana Paula Monezzi Teixeira, Jhéssica Letícia Santos Santana, Raquel Acácia Pereira Gonçalves Santos & Regiane Patussi Santos Lima·Asian Journal of Immunology·2023
Aims: To evaluate the potential of the Leukocyte Adherence Inhibition Test (LAIT) to discriminate non–IgE-mediated innate immunoreactivity against Saccharomyces cerevisiae in patients with clinical suspicion of allergic reaction to fungal allergens. Study Design: We retrospective...
Celso Eduardo Olivier, Daiana Guedes Pinto, Ana Paula Monezzi Teixeira, Jhéssica Letícia Santos Santana, Raquel Acácia Pereira Gonçalves Santos & Regiane Patussi Santos Lima·Asian Journal of Immunology·2023
Aims: To evaluate the potential of the Leukocyte Adherence Inhibition Test (LAIT) for evaluating immunoreactivity against cochineal dye (E120) in patients with clinical suspicion of symptomatic hypersensitivity to this food additive. Study Design: We retrospectively examined the...
Celso Eduardo Olivier, Daiana Guedes Pinto, Ana Paula Monezzi Teixeira, Jhéssica Letícia Santos Santana, Raquel Acácia Pereira Gonçalves Santos & Regiane Patussi Santos Lima·Asian Journal of Immunology·2023
Aims: To evaluate the potential of the Leukocyte Adherence Inhibition Test (LAIT) as a tool for evaluating immunoreactivity against cobalt in patients with clinical suspicion of cobalt hypersensitivity. Study Design: We retrospectively examined the medical charts of a population...
Celso Eduardo Olivier, Daiana Guedes Pinto, Ana Paula Monezzi Teixeira, Jhéssica Letícia Santos Santana, Gabriela Silva de Brito, Raquel Acácia Pereira Gonçalves Santos, Regiane Patussi Santos Lima & Everton Salgado Monteiro·Asian Journal of Immunology·2023
Aims: To evaluate the contribution of non—IgE-mediated hypersensitivity mechanisms in Papular Urticaria produced by Aedes spp and Culex spp bites in patients diagnosed with Intrinsic Atopic Dermatitis coming from an urban (not beachy) Brazilian region. Study Design: To better und...
Celso Eduardo Olivier, Daiana Guedes Pinto, Ana Paula Monezzi Teixeira, Jhéssica Letícia Santos Santana, Raquel Acácia Pereira Gonçalves Santos & Regiane Patussi Santos Lima·Asian Journal of Immunology·2023
Aims: To evaluate the potential of the Leukocyte Adherence Inhibition Test (LAIT) as a diagnostic tool for nickel sensitization in patients with clinical suspicion of Nickel Hypersensitivity (NiH). Study Design: We retrospectively examined the medical charts of a population of 10...
Celso Eduardo Olivier, Daiana Guedes Pinto, Ana Paula Monezzi Teixeira, Jhéssica Letícia Santos Santana, Raquel Acácia Pereira Gonçalves Santos, Regiane Patussi Santos Lima & Everton Salgado Monteiro·Asian Journal of Immunology·2023
Aims: Medical literature defines the diagnosis of “selective IgE deficiency” (sIgEd) as the individuals able to produce, at normal amounts, all antibodies’ classes, and subclasses, with exception of the IgE, which is not found by the laboratory detection method (usually below 2.0...