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Chandima Kulathilake

Publications (4)

Correlation between PT/INR and APTT in Patients on Warfarin: A Study at a Tertiary Care Teaching Hospital

Sasini Attanayake, Ishara Manathunga & Chandima Kulathilake · Asian Hematology Research Journal · 2023

Background: Warfarin prolongs coagulation by inhibiting the synthesis of biologically active forms of coagulation factors and regulatory factors, which are dependent on vitamin K. The Prothrombin Time (PT) and International Normalized Ratio (INR) are routinely used to monitor war...

Open access Research Article

Evaluation of One Tube Osmotic Fragility as a Screening Test for Beta Thalassaemia Trait

Akila Pilapitiya, Mylvaganam Thayaparan, Chandima Kulathilake, Rohini Warushahennadi & Jiffry Nilam · Asian Journal of Medical Principles and Clinical Practice · 2021

Background: Thalassaemia is highly prevalent in Sri Lanka. The highest number of patients are seen in the North Western province, especially in the Kurunegala district. Screening of children and adults to detect beta thalassaemia carriers/trait using automated full blood counts a...

Open access Research Article

Relationship between HAS-BLED Score & Major Bleeding Events in Patients with Non-valvular Atrial Fibrillation on Warfarin: A Study at a Tertiary Care Teaching Hospital

Vishwa Lokuhettige, Prabath Chathuranga, Chandima Kulathilake, Nishadya Ranasinghe, Sampatha Goonewardena & Vindya Kumarapeli · Asian Hematology Research Journal · 2020

Background: Prevention of stroke and thrombo-embolism in patients with atrial fibrillation(AF) using oral vitamin K antagonists is closely related to risk of bleeding. The HAS-BLED score has been evaluated as a predictor of major bleeding risk in various populations. The present...

Open access Research Article

Assessment of Full Blood Count Parameters in Patients with End Stage Renal Disease (ESRD) on Regular Haemodialysis

Tharindu Alagiyawanna, Sajani Ranawaka, Piumanthi Karunarathne & Chandima Kulathilake · Asian Journal of Research in Nephrology · 2020

Background: Haematological profile is commonly affected in chronic kidney disease and this becomes more apparent as the disease progresses. The aim of this study was to assess full blood count (FBC) parameters in a cohort of Sri Lankan patients with End Stage Renal disease (ESRD)...

Open access Research Article