Charles Guillaume Kodjo

Theoretical Study of the Chemical Reactivity of Five Schiff Bases Derived From Dapsone by the DFT Method

Jean Stéphane N’dri, Mamadou Guy-Richard Koné, Charles Guillaume Kodjo, Ahmont Landry Claude kablan, Sopi Thomas Affi, Lamoussa Ouattara & Nahossé Ziao · Chemical Science International Journal · 2018

This theoretical study of chemical reactivity was conducted using the method of the Density Functional Theory (DFT), with B3LYP/6-311G (d, p) as calculation level. A series of five (05) Schiff bases derived from 4.4 '-diaminodiphenylsulfone (Dapsone) was concerned and allowed to...

Open access Research Article 10.9734/CSJI/2018/41427

Design and ADMET Study of New Theoretical Molecules of Thiourea Derivatives with Potential Anticancer Activities of the Breast of the MCF-7 Strain

Siriki DOUMBIA, Niameke Jea Baptiste KANGAH, Georges Stephane Dembele, Nanou Tieba Tuo & Charles Guillaume Kodjo · Chemical Science International Journal · 2025

The objective of this work is to design in silico new thiourea derivatives with improved potential anticancer activities of the breast of the MCF-7 strain. Fifty (50) new molecules were generated. All the generated compounds belong to the applicability domain of the model. Only t...

Open access Research Article 10.9734/CSJI/2025/v34i5998

Theoretical Study of the Chemical Reactivity of a Series of 2, 3-Dihydro-1H-Perimidine

Nanou Tieba Tuo, Georges Stephane Dembele, Soro Doh, Fandia Konate, Bibata Konate, Charles Guillaume Kodjo & Nahossé Ziao · International Research Journal of Pure and Applied Chemistry · 2022

This reactivity study was performed on seven molecules of a 2,3-dihydro-1H-perimidine series using density functional theory at the B3LYP / 6-311 G (d, p) level. Calculation of the dipole moment showed that compound 4 is more soluble in aqueous medium. The study of frontier molec...

Open access Research Article 10.9734/irjpac/2022/v23i130451