Christian Ajiri Adobor

Gene Editing in Cancer Immunotherapy: Mechanisms, Advancements, Limitations and Future Directions

Lawrence John AJutor, Okabeonye Sunday Agbo, Christian Ajiri Adobor, Blessing Aitebiereme Iyoyojie, Kingsley Ugonna Ugoagwu, Oghenevware Manawa, Osaruese Faluyi, Emmanuel Oluwasegun Ismaila, Oluchi Esther Ugwuanyi & Adepeju Matilda Adekoya · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2024

Gene editing has emerged as a transformative approach in cancer immunotherapy. Several gene editing tools have been employed for precise modification of the DNA of immune cells, enhancing their ability to target and eliminate cancer cells. This review examines the evolution and a...

Open access Research Article 10.9734/ajbgmb/2024/v16i12428

Role of Immune Checkpoints (PD-1, PDL1 and CTLA-4) In Triple-Negative Breast Cancer and Therapeutic Implications

Lawrence John AJutor, Blessing Aitebiereme Iyoyojie, Kingsley Ugonna Ugoagwu, Orkaa Terungwa Samuel, Olufemi Adesola Adedayo, Daniel Temiloluwa Oyedemi, Daniel Ebubechi Obasi, Adegbesan Abiodun Christopher, Adewoyin Peter Bemigho & Christian Ajiri Adobor · International Research Journal of Oncology · 2025

Triple-negative breast cancer (TNBC) is one of the most prominent types of breast cancer. It is a very aggressive subtype that is characterized by the absence of certain receptors which are expected on the surface of tumor cells. Limited treatment options and a poor prognosis, hi...

Open access Research Article 10.9734/irjo/2025/v8i1170