Aims: Paeoniflorin exhibits a broad range of in vitro and in vivo pharmacological effects. However, its potential as a drug targeting adenosine receptors remains largely unexplored. Methodology: In this study, the wild-type N2 strain and the Ador-1 gene knockout EG6890 strain of...
Open access
Research Article10.9734/arrb/2025/v40i42219
Aims: Adenosine and salidroside exert both preventive and therapeutic effects on neurodegenerative diseases, including Alzheimer's and Parkinson's diseases. However, the mechanism is unclear. Methodology: N2 wild-type and EG6890 (Ador-1 gene knockout) Caenorhabditis elegans were...
Open access
Research Article10.9734/arrb/2025/v40i32211
Aims: This study aims to investigate the impact of lactate and adenosine, present in the tumor microenvironment (TME), on the immune cell immunity. Methodology: Five groups included Adenosine concentration screening groups, L-lactic acid and Sodium L-lactate concentration groups,...
Open access
Research Article10.9734/arrb/2024/v39i32062
Aims: Lactate acid functions as not only an energy source but a signaling molecule through the lactate receptor GPR81 under physiological conditions. However, the pathological role of lactic acid in the tumor microenvironment remains unclear, particularly for immune cells. Method...
Open access
Research Article10.9734/arrb/2023/v38i330573
Aims: Polysaccharides have shown efficacy in a broad range of applications, especially in immune regulation. However, there are only few effective methods available to evaluate and compare the immunoregulatory properties of the different polysaccharides in vitro. To screen string...
Open access
Research Article10.9734/arrb/2021/v36i430365
Aims: This study aimed to establish an acoustic levitation-based microgravity simulation model and investigate its effects on the locomotor function and muscle protein expression of Caenorhabditis elegans. Methodology: L4-stage N2 nematodes were assessed on gel ball and on cultur...
Open access
Research Article10.9734/arrb/2025/v40i52239
Aims: Mildew poses a significant threat to tobacco industry. This study focuses on a strain of Cladosporium asperulatum isolated from moldy tobacco leaves to investigate its growth under different temperature and humidity conditions, aiming to provide a theoretical basis for loca...
Open access
Research Article10.9734/arrb/2024/v39i32066