Craig Delury

Differential Regulation of E-Cadherin Expression by the Soluble Ectodomain and Intracellular Domain of Jagged1

Craig Delury, Claire Tinker, Samantha Rivers, Matthew Hodges, Susan Broughton & Edward Parkin · International Journal of Biochemistry Research & Review · 2013

Aberrant Jagged1-mediated Notch activation is linked to cancer and induces epithelial-to-mesenchymal transition through the repression of E-cadherin transcription. All three proteins are subject to sequential proteolytic events referred to as regulated intramembrane proteolysis....

Open access Research Article 10.9734/IJBCRR/2013/3847

The E1 Copper Binding Domain of Full-Length Amyloid Precursor Protein Promotes Epithelial to Mesenchymal Transition in DU145 Cells in an Isoform-Specific Manner

Mallory Gough, Craig Delury & Edward Parkin · International Journal of Biochemistry Research & Review · 2014

The E1 Copper Binding Domain of Full-Length Amyloid Precursor Protein Promotes Epithelial to Mesenchymal Transition in DU145 Cells in an Isoform-Specific Manner Epithelial to mesenchymal transition (EMT) confers migratory and dynamic properties on cells and, as such, plays a pivo...

Open access Research Article 10.9734/IJBCRR/2015/14873