D. O. Wakeel

Anti Epileptogenic Potential of Ethanol Leaf Extract of Pygeum africanum in Mice

O. K. Wakeel, Okoduwa J. Omoabhiena, D. O. Wakeel, Akeem A. Ayankunle, Timothy O. Kolawole, Oluwasewa O. Ademola & Samuel A. Ademola · Journal of Complementary and Alternative Medical Research · 2025

Several current pharmaceuticals are derived from medicinal plants, either in pure or semisynthetic forms. Drug discovery via natural product research has long been fruitful. Traditionally, Pygeum africanum (PA) is used to treat various ailments in Africa. This study explores the...

Open access Research Article 10.9734/jocamr/2025/v26i8691

Role of Gabanergic and, or Serotonergic in the Anti-seizure Activity of Methanol Extract of Crinum jagus (J. Thomps) in Experimental Mice

O. K. Wakeel, R. A. Adebayo-Moggaji, D. O. Wakeel, O. O. Abiodun, O. T. Kolawole, A. Y. Onaolapo, O. J. Onaolapo & H. G. Subbair · European Journal of Medicinal Plants · 2022

Objective: Crinum jagus is used in traditional African medicine in the treatment of epilepsy, pain and inflammations. Methods: Anticonvulsant activity was investigated using picrotoxin (PCT) and strychnine (STR) tests in experimental paradigm. Results: Crinum jagus leaf methanol...

Open access Research Article 10.9734/ejmp/2022/v33i430461