Daniel Obi

ABT-263, an Inhibitor of Bcl-2 Family Antiapoptotic Proteins, Sensitizes Prometaphase-Arrested HeLa Cells to Apoptosis Induced by Mild Hyperthermia

James R. Paulson, Rachel L. Luedtke, Savannah Suydam, Daniel Obi & Linfeng Xie · International Journal of Biochemistry Research & Review · 2022

Aims: We have previously shown that mild hyperthermia (39-42°C) rapidly induces apoptosis in H-HeLa cells arrested in mitosis but not in interphase cells and not in mitotic-arrested cells of other HeLa strains such as HeLa S3.  Our goal was to test the idea that this sensitivity...