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E. O. Wellington

Publications (5)

Nephrotoxicity Screening of Aqueous Extract of Commelina diffusa in Non-Pregnant Female Wistar Rats: Acute to Chronic Exposure

E. O. Wellington, D. J. Elvis & G. I. Dighemedim · Journal of Applied Life Sciences International · 2026

Nephrotoxicity is the immediate degeneration in the kidney activity arising from the toxic effect of medications and chemicals. Commelina diffusa is a medicinal herb that has long been used to treat a variety of ailments, however, its nephrotoxic effect has not been scientificall...

Open access Research Article 10.9734/jalsi/2026/v29i2770

Ameliorative Effect of Aqueous Crude Extract of the Aerial Parts of Leonurus Cardiaca on Doxorubicin-Induced Cardiovascular Damage in Wistar Rats

E. O. Wellington, M. B. Otobo & S. J. Ogbomade · International Journal of Biochemistry Research & Review · 2023

This study investigated the ameliorative effect of aqueous crude extract of the aerial parts of Leonurus cardiaca on doxorubicin-induced cardiovascular damage in Wistar rats. Aqueous crude extract of Leonurus cardiaca was prepared based on standard Laboratory condition. A total o...

Open access Research Article 10.9734/ijbcrr/2023/v32i6820

Acute, Sub-acute and Chronic Toxicity Evaluation of Aqueous Extract of the Aerial Parts of Leonurus cardiaca in Normal Non-pregnant Female Wistar Albino Rats per OECD 425 TG

E. O. Wellington, E. N. Onyeike, D. E. Peters, M. B. Otobo, D. Felix & S. J. Ogbomade · Journal of Applied Life Sciences International · 2022

This study graded the acute, sub-acute, and chronic toxicity of aqueous extract of the aerial parts of Leonurus cardiaca in non-pregnant female wistar rats. Fifty wistar albino rats weighing between 180 and 200g were used for this study. The rats were grouped into 10 groups of fi...

Open access Research Article 10.9734/jalsi/2022/v25i6580

Phytochemical Composition and Hepatoprotective Potential of Ethanolic Root Extract of Jatropha curcas in Acetaminophen-Induced Toxicity in Albino Wistar Rats

D. Felix, C. U. Ogunka-Nnoka & E. O. Wellington · Journal of Applied Life Sciences International · 2022

This study evaluated the phytochemical composition and hepatoprotective potential of ethanolic root extract of Jatropha curcas in acetaminophen-induced toxicity in wistar albino rats. The phytochemical screening and composition were determined using gas chromatography. Thirty alb...

Open access Research Article 10.9734/jalsi/2022/v25i530304

Ameliorative Effect of Ethanolic Fruit Extract of Perssea americana and Prunus dulcis on Caffein-Testicular Damage in Male Wistar Albino Rats

M. B. Otobo, J. O. Akaninwor, B. A. Amadi & E. O. Wellington · International Journal of Biochemistry Research & Review · 2022

This study investigated the effect if ethanolic fruit extracts of Perssea americana and Prunus dulcis on caffeine-testicular damage in male albino rats. Sixty rats weighing 120 and 170 g were used for this study. The rats were separated into 12 groups of five rats per group. Grou...

Open access Research Article 10.9734/ijbcrr/2022/v31i630331