The Role of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) in Recognition of Pseudomonas aeruginosa in Lung Epithelial Cells
Ekong, Mercy Okon, Tarh, Jacqueline Ebob & Iroegbu, Christian Ukwuoma · Asian Journal of Biotechnology and Genetic Engineering · 2018
Cystic Fibrosis Transmembrane Regulator (CFTR) plays an important role in chloride and thiocyanate ion homeostasis in human epithelial surfaces. Deletion of phenylalanine at position 508 (Δ508) leads to cystic fibrosis and dysregulation of pro-inflammatory cytokines. Pseudomonas...
Open access
Research Article