Maria E. Filkina, Lev A. Lintsov, Victor A. Tafeenko, Maxim E. Kukushkin & Elena K. Beloglazkina·Organics·2026
1,3-Dipolar cycloaddition reactions of nitrile imines are a powerful tool for the construction of spirocyclic frameworks, yet controlling chemoselectivity remains challenging when dipolarophiles contain multiple reactive sites. In this study, we investigated the cycloaddition of...
Xiumei Bai, Danila R. Chernyavskiy, Anna D. Maksimova, Ilya A. Yakushev, Viktor A. Tafeenko, Elena K. Beloglazkina & Alexander V. Finko·Organics·2026
We report the synthesis and single-crystal X-ray structures of three novel (Z)-5-arylidene-3-phenylrhodanine derivatives, differing in the substituents on the benzylidene fragment (two methoxy groups (compound I), a dioxine ring (compound II), or a dioxole ring (compound III)). D...
Aleksei E. Machulkin, Stanislav A. Petrov, Maria D. Kraynova, Anastasiia S. Garanina, Bayirta V. Egorova, Roman V. Timoshenko, Alexander N. Vaneev, Alexander S. Erofeev, Anna B. Priselkova, Mikhail A. Kalinin, Aleksei V. Medved’ko, Stepan N. Kalmykov, Elena K. Beloglazkina & Sergey Z. Vatsadze·Organics·2025
Nowadays, PSMA ligands are widely used for radiotheragnostic purposes in prostate cancer. The synthesis of a PSMA-Bisp conjugate was developed and realized with good yield (overall yield ~58% for the last two steps). All newly synthesized compounds were characterized by physicoch...