Erten Akbel

Chromatographic Method for Quantification of Tenofovir in Pharmaceutical Formulations: Comparison with Spectrophotometric Method

Erten Akbel & İbrahim Bulduk · Journal of Pharmaceutical Research International · 2021

Aims: An efficient therapeutic drug or antiviral agent to treat Covid-19 is still not available. But, previously licensed pharmaceuticals to treat other virus infections are usedon an off-label basis either alone or in combination. Tenofovir emerged as a promising treatment for C...

Open access Research Article 10.9734/jpri/2021/v33i49A33330

A Simple LC-MS/MS Method for Determination of Vemurafenib in Rat Plasma Fed with High Fat Diet

Ayşe Özdemir, Senem Şanli & Erten Akbel · Journal of Pharmaceutical Research International · 2021

In this study, high fat diet was fed to rats and the amount of vemurafenib in rat plasma was determined by the developed liquid chromatography with tandem mass spectrometry. The calibration curve was linear between 0.01 and 0.8 µg mL−1 vemurafenib with 0.999 regression coefficien...

Open access Research Article 10.9734/jpri/2021/v33i40B32285