F. C. Kenechukwu

Controlled Release Binary and Ternary HPMC-HPC-Gelucire® 50/13 Hybrids Based Solid Dispersions of Indomethacin: In vitro Evaluation and In vivo Anti-inflammatory Studies

J. N. Reginald-Opara, K. C. Ofokansi, F. C. Kenechukwu, C. G. Nwaigwe & A. M. Nnogo · Journal of Pharmaceutical Research International · 2018

Aim: The aim of this study is to formulate and evaluate solid dispersions of indomethacin based on Gelucire 50/13, Hydroxylpropyl methylcellulose and/or Hydroxylpropyl cellulose hybrid binary or ternary system, with a view of enhancing oral bioavailability, sustaining drug releas...

Open access Research Article 10.9734/JPRI/2018/22643

Formulation, in vitro and in vivo Characterisation of Diclofenac Potassium Sustained Release Tablets Based on Solidified Reverse Micellar Solution (SRMS)

S. A. Chime, A. A. Attama, F. C. Kenechukwu, E. C. Umeyor & G. C. Onunkwo · Journal of Pharmaceutical Research International · 2013

Aims: To formulate sustained release diclofenac potassium tablets based on solidified reverse micellar solution (SRMS) and to evaluate the in vitro and in vivo properties of the tablets. Study Design: Formulation, in vitro and in vivo evaluation of sustained release diclofenac po...

Open access Research Article 10.9734/BJPR/2013/1567

Distribution of Methicillin-Resistant Staphylococcus aureus (MRSA) in Apparently Healthy Population and its Susceptibility to Saponins from Dialium guineense

W. O. Obonga, C. O. Nnadi, M. O. Agbo, F. C. Kenechukwu & U. Nwodo · Journal of Pharmaceutical Research International · 2014

Aims: The ethanolic extracts of stem bark and fruit pulp as well as saponins from Dialium guineense were assayed for antibacterial activity against Gram positive and negative strains and clinical strains of methicilin resistant Staphylococcus aureus (MRSA) isolated from different...

Open access Research Article 10.9734/BJPR/2014/12943