Fernando Martins Castanheira Júnior

Haloperidol as a Novel Augmentation Strategy in Treatment-Resistant Depression: A Clinical Practice Perspective with Case Series

Giovanna Azevedo Rodrigues, Fernando Martins Castanheira Júnior, Luiz Costa & Marcelo Caixeta · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2026

Treatment-resistant depression (TRD) remains a major clinical challenge when adequate antidepressant trials fail to achieve remission. This clinical practice perspective examines low-dose haloperidol as a potential augmentation strategy in carefully selected, treatment-refractory...

Open access Research Article 10.9734/ajrimps/2026/v15i4418

The General Psychiatric Syndrome as a Transdiagnostic Hypothesis: A Critical Appraisal of Evidence, Interpretation and Clinical Reach

Luiz Costa, Fernando Martins Castanheira Júnior, Giovanna Azevedo Rodrigues & Marcelo Caixeta · International Neuropsychiatric Disease Journal · 2026

Persistent comorbidity, diagnostic instability and the scarcity of disorder-specific causes have encouraged the proposal that a single superordinate dimension underlies liability to all common mental disorders. This proposition, expressed empirically as the general factor of psyc...

Open access Research Article 10.9734/indj/2026/v23i5581

The Kinesthetic-motor Hypothesis in Developmental Dyslexia: A Systematic Review and Theoretical Model Proposition

Giovanna Azevedo Rodrigues, Fernando Martins Castanheira Júnior, Luiz Costa & Marcelo Caixeta · International Neuropsychiatric Disease Journal · 2026

Introduction: Developmental dyslexia is traditionally explained by the acoustic phonological deficit theory, yet clinical observations suggest that reading difficulties may extend to motor and articulatory components, manifesting as phono-articulatory stalls during the decoding o...

Open access Research Article 10.9734/indj/2026/v23i5577

Provisional Early-onset Bipolar Disorder with Phonological Reading Disorder and Attachment-related Difficulties in a Child Exposed to Severe Parental Conflict: A Case Report

Giovanna Azevedo Rodrigues, Fernando Martins Castanheira Júnior, Luiz Costa & Marcelo Caixeta · International Neuropsychiatric Disease Journal · 2026

Background: Severe mood dysregulation in childhood requires careful differentiation among episodic bipolar-spectrum illness, chronic irritability, trauma-related responses, anxiety, neurodevelopmental conditions, sleep disturbance, and environmental stress. Diagnostic uncertainty...

Open access Research Article 10.9734/indj/2026/v23i4572