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Great David Bagu

Publications (4)

Moringa oleifera Leaf Extract Promotes Antioxidant, Survival, Fecundity, and Locomotor Activities in Drosophila melanogaster

Walter Mdekera Iorjiim, Simeon Omale, Great David Bagu, Steven Samuel Gyang & Emmanuel Taiwo Alemika · European Journal of Medicinal Plants · 2020

Aim: The study was designed to investigate antioxidant, survivability,  fecundity, and locomotor activity of Moringa oleifera leaf (MOL) extract in Drosophila melanogaster. Materials and Methods: The study was conducted at the Africa Centre of Excellence in phytomedicine Research...

Open access Research Article 10.9734/ejmp/2020/v31i1530322

Reproductive and Oxidative Stress Toxicity of Dolutegravir-Based Combination Antiretroviral Therapy in Drosophila melanogaster

Walter Mdekera Iorjiim, Simeon Omale, Great David Bagu, Steven Samuel Gyang & Emmanuel Taiwo Alemika · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

Background/Objective: Dolutegravir-based highly active antiretroviral therapy (DTG-HAART) is the preferred regimen in the management of HIV/AIDS. However, the reproductive and oxidative stress toxicity of DTG-HAART is unknown.  This study was designed to investigate the reproduct...

Open access Research Article 10.9734/jamps/2020/v22i630177

Highly Active Antiretroviral Therapy Depletes Some Antioxidant Parameters and Increases Free Radical Generation in Drosophila melanogaster

Walter Mdekera Iorjiim, Simeon Omale, Great David Bagu, Steven Samuel Gyang, Emmanuel Taiwo Alemika & Monday Alexander Etuh · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

Objective: This study intended to evaluate the toxic effects of Efavirenz-based highly active antiretroviral therapy (EFVb-HAART) on some antioxidant parameters, and free radical generation in D. melanogaster. Materials and Methods: The study was carried out at the Centre of Exce...

Open access Research Article 10.9734/jamps/2020/v22i230158

EFVb-HAART Increases Mortality, Locomotor Deficits and Reduces Reproductive Capacity in Drosophila melanogaster

Walter Mdekera Iorjiim, Simeon Omale, Monday Alexander Etuh, Great David Bagu, Sunshine Ochala Ogwu & Steven Samuel Gyang · Journal of Advances in Biology & Biotechnology · 2020

Aims: This study was designed to evaluate the effects of Efavirenz-based highly active antiretroviral therapy (EFVb-HAART, Efavirenz/Lamivudine/Tenofovir) with emphasis on survival, longevity, climbing ability, and reproductive capacity in D. melanogaster. Methods: The experiment...

Open access Research Article 10.9734/jabb/2020/v23i130136