Hajer Almamri

Exploring Gene Therapy Strategies for Cystic Fibrosis: A Comprehensive Review of CFTR Gene Mutations, Bioinformatics Analysis, and Emerging Therapeutic Approaches

Hassan S. Darwish, Hajer Almamri, Manohar Noone, Azher Alhabsi & Una Gibbons · Biotechnology Journal International · 2024

Aim: This study aimed to identify the most promising gene therapy approach for treating patients with cystic fibrosis. Background: Cystic fibrosis is a rare autosomal recessive disorder affecting malabsorption, malnutrition, and lung function. It results from genetic mutations in...

Open access Research Article 10.9734/bji/2024/v28i1713

Bioinformatics Analysis of LDLR Gene Mutation that Shed a New Light on Red Yeast Rice Monacolin K Treatment – Systematic Review

Hassan Sadek Darwish, Hajer Almamri, Ray Barazie & Mohammed Mustafa · Annual Research & Review in Biology · 2022

Background: Hypercholesteremia is the major cause of cardiovascular diseases. It results from elevated cholesterol levels in the blood. LDL cholesterol is removed from the circulation by using the LDL receptor. Red mold rice or red yeast rice is produced by fermentation of the Mo...

Open access Research Article 10.9734/arrb/2022/v37i730521

Genomic Study of TCF7L2 Gene Mutation on Insulin Secretion for Type 2 DM Patients: A Review

Hassan S. Darwish, Badriya Alrahbi, Hajer Almamri, Manohar Noone, Hussam Osman & Ashgan Abdelhalim · Annual Research & Review in Biology · 2022

Aim: This paper aims to establish whether a correlation between TCF7L2 gene mutation on insulin secretion for Type 2 DM Patients. Background: Diabetes type 2 is the most common metabolic disorder worldwide. Beta cell dysfunction reduces insulin secretion and increases the glucose...

Open access Research Article 10.9734/arrb/2022/v37i1230560