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Hemanth Kumar Manikyam

Publications (4)

Intrinsic Network Pharmacology for Mapping Divergent System Trajectories: Computational Study of Rasayana Induced Restoration and Deficiency Driven Collapse

Hemanth Kumar Manikyam & Sunil K. Joshi · Archives of Current Research International · 2025

Contemporary chronic diseases, including pervasive Vitamin D3 and B12 deficiencies, are increasingly considered failures of intricate metabolic and regulatory networks—rather than isolated biochemical imbalance. Deficiencies interrupt integrated processes such as redox signaling,...

Open access Research Article 10.9734/acri/2025/v25i61281

Supercritical CO2 Extraction and HPLC Quantification of Carnosic Acid from the leaves of Rosemary Officinalis: A Green Approach to Bioactive Compound Purification

Hemanth Kumar Manikyam, Dhanaseelan J & Jayaraj Mani · Chemical Science International Journal · 2024

This study explores the extraction and purification of carnosic acid, a potent antioxidant found in rosemary (Rosmarinus officinalis), using a green and sustainable method involving supercritical CO₂. The extraction was conducted at 45°C and 350 bar, with three cycles lasting 45...

Open access Research Article 10.9734/CSJI/2024/v33i6920

Cryoethanolic Extraction, Purification of Allicin from Allium sativum and HPTLC analysis

Hemanth Kumar Manikyam, Dhanaseelan J & Jayaraj Mani · International Journal of Biochemistry Research & Review · 2024

The significance of this research extends beyond the mere extraction and purification of allicin, encompassing its potential applications across diverse industries. Allicin exhibits a plethora of biological activities, including antimicrobial, antifungal, antiviral, and antiproto...

Open access Research Article 10.9734/ijbcrr/2024/v33i6887

Ergot Alkaloids: A Review on Therapeutic Applications

Niti Sharma, Vinay K. Sharma, Hemanth Kumar Manikyam & Acharya Bal Krishna · European Journal of Medicinal Plants · 2016

Ergot of Rye is a plant disease caused by the fungus Claviceps purpurea which infects the grains of cereals and grasses but it is being used for ages for its medicinal properties. All the naturally obtained ergot alkaloids contain tetracyclic ergoline ring system, which makes the...

Open access Research Article 10.9734/EJMP/2016/25975