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Ian Jhemes Oliveira Sousa

Publications (4)

Design and In silico Validation of Primers for Assessing Gene Expression in the Canonical Inflammatory Pathway

Ian Jhemes Oliveira Sousa, Kerolayne de Melo Nogueira, Higo José Neri da Silva & Ester Miranda Pereira · Advances in Research · 2025

Aims: This study aimed to design and validate primers to investigate the expression of key genes of the canonical inflammation pathway, specifically NEMO (NF-kappaB Essential Modulator), MyD88 and IL-1β, in order to ensure feasibility, specificity and efficiency for use in RT-qPC...

Open access Research Article 10.9734/air/2025/v26i11265

Mechanisms Underlying Weight Regain After GLP-1RA Treatment: A Neurobiological Perspective

Kerolayne de Melo Nogueira & Ian Jhemes Oliveira Sousa · Annual Research & Review in Biology · 2026

Weight rebound after discontinuation of GLP-1 receptor agonists (GLP-1RAs) is common and often misinterpreted as a sign of weak willpower. This review summarizes preclinical and clinical evidence on how GLP-1RAs affect food stimulus processing and other systems that determine rel...

Open access Research Article 10.9734/arrb/2026/v41i12370

Epidemiological Profile of Patients with Cutaneous Leishmaniasis in Maranhão State, Brazil

Maria Eduarda Santos Ferreira, Fernanda da Silva Ferreira, Keylla da Silva Machado, Rodrigo Lopes Gomes Gonçalves & Ian Jhemes Oliveira Sousa · Advances in Research · 2025

Aims: The present study aims to observe the epidemiological factors that lead to the high occurrence of Leishmaniasis cases in Brazil, highlighting the endemic area of Maranhão, the main factors involved in its transmission, the challenges for controlling the disease and the pros...

Open access Research Article 10.9734/air/2025/v26i41392

Analysis of the Epidemiological Impact of a Public Health Policy against Meningococcal Meningitis in Children in Maranhão, Brazil

Maria Eduarda Brilhante Bandeira, João Arthur Soares de Sousa Teixeira, Anna Taynah Milhomem Rodrigues, Kawanny Evellyn Reis Félix de Oliveira, Ana Beatriz Mendes Rodrigues & Ian Jhemes Oliveira Sousa · Advances in Research · 2025

Aims: Over the years, Meningococcal Disease (MD), an acute infection characterized by inflammation of the meninges in response to the agent N. meningitidis, has been affecting different regions of Brazil in different ways. Therefore, the meningococcal C vaccine (MeCV) was introdu...

Open access Research Article 10.9734/air/2025/v26i31373