Severe Hemolytic Anemia Due to De novo Hemoglobin Sabine in an Argentinian Newborn. First Case in South America
Susana Perez, Irma Bragós, Mariana Raviola, Arianna Pratti, Germán Detarsio, Sandra Zirone, Maria Eda Voss, Luciano Verón, Irma Acosta & Mara Ojeda · International Blood Research & Reviews · 2015
Hemoglobin (Hb) Sabine is an unstable Hb variant that causes hemolytic anemia in heterozygous state, with inclusion bodies in the red blood cells (RBC). This hemoglobin is the result of a point mutation at codon 91(CTG)®(CCG) of the beta-globin gene. We report, for the first time...
Open access
Research Article
10.9734/IBRR/2015/18559