Ishmael B. Masesane

Room Temperature Na2CO3-Catalysed One-pot Reaction of Benzaldehydes, Malononitrile and Phloroglucinol in Water, a Simple Green Synthetic Route to Antibacterial 2-Amino-4H-Benzopyrans

Ishmael B. Masesane & Shetonde O. Mihigo · International Research Journal of Pure and Applied Chemistry · 2015

A simple and green room temperature Na2CO3-catalysed three-component reaction of benzaldehydes, malononitrile and phloroglucinol in water to give 2-amino-4H-benzopyrans in 70-96% yields is described. The reaction was tolerated by electron-donating and electron-withdrawing substit...

Open access Research Article 10.9734/IRJPAC/2015/20066

Investigation of the H3PO4-Promoted Reaction of Benzaldehydes, Ethyl Acetoacetate or Ethyl Cyanoacetate or Malononitrile in the Presence of Urea as a Route to Pyrimidin-2-ones and 2-Iminochromenes

Ishmael B. Masesane, Ngonye Keroletswe & Runner R. Majinda · International Research Journal of Pure and Applied Chemistry · 2015

The H3PO4-promoted reactions of benzaldehydes, active methylene compounds and urea are reported. Benzaldehydes, ethyl acetoacetate and urea react in the presence of H3PO4 to give substituted pyrimidin-2-ones in 49-84% yields. The three-component reaction failed when either ethyl...

Open access Research Article 10.9734/IRJPAC/2015/20189