Islam Ariremako Jimoh

The Gut–NET–ICB Axis: Microbial Metabolite-Mediated Regulation of NETosis and Implications for Cancer Immunotherapy

Islam Ariremako Jimoh, TOBECHI BRENDAN NNANNA, TAIWO MICHEAL OLUMUJI, Paul Onyekachi Ukegbu, Michael Sewanu Hungbo & Kanime Hussaini · Asian Journal of Immunology · 2025

Background: Immune checkpoint blockade (ICB) has transformed oncology, but its efficacy is limited by primary and acquired resistance. The gut microbiome is a established determinant of ICB response, while neutrophil extracellular traps (NETs) have recently emerged as key mediato...

Open access Research Article 10.9734/aji/2025/v8i1177

Role of Gut Microbiota-Derived Metabolites in Modulating Immune Responses in Colorectal Cancer

Adedoyin Elizabeth Ayodele, Peace Chibuogwu Ugama, Tobiloba Philip Olatokun, Islam Ariremako Jimoh, Blessing Oluwapelumi Oyebamjji & Raimot Efunyinka Junaid-Eko · International Journal of Pathogen Research · 2025

Colorectal cancer (CRC) is a leading cause of global cancer mortality, with its incidence rising due to environmental and lifestyle factors. The gut microbiota influence CRC pathogenesis through the production of bioactive metabolites that modulate the host immune response. This...

Open access Research Article 10.9734/ijpr/2025/v14i5400