Ismael de Sousa Armondes

Molecular Pathogenesis and Targeted Therapeutic Advances in Langerhans Cell Histiocytosis: A Systematic Review

Roger Antonio Morais Queiroz, Gabriela Aguiar Rezende, Ismael de Sousa Armondes, Joaquim Alberto Lopes Ferreira Junior, João Protásio Netto, Fernando Macena Lino, Yasmim Batista de Paiva, Cássio Luis Tavares Dias, Vagner Carmargo Pires & Regina de Fátima Mendes Onofre · Advances in Research · 2026

Introduction: Langerhans Cell Histiocytosis (LCH) is a rare myeloid neoplasm characterized by clonal proliferation of immature dendritic cells, primarily driven by constitutive activation of the MAPK signaling pathway through mutations in BRAFV600E, MAP2K1, and ARAF. Recent genom...

Open access Research Article 10.9734/air/2026/v27i11572

Hormonal Changes in Menopause and Musculoskeletal Health: Evidence from a Systematic Review

Roger Antonio Morais Queiroz, Hélio Rovilson Soares, Aline Alencar de Andrade Bressan, Vitória Vaz Guimarães, Valdir Francisco Odorizzi Covre, Vagner Camargo Pires, Ismael de Sousa Armondes, Joaquim Alberto Lopes Ferreira Junior, Mariana Mantovani Marciano & Andressa Coelho dos Santos · Advances in Research · 2026

Introduction: Menopause is a physiological stage of female aging characterized by a decline in estrogen levels, leading to systemic changes that significantly affect musculoskeletal health. These hormonal alterations are associated with increased risk of osteoporosis, sarcopenia,...

Open access Research Article 10.9734/air/2026/v27i31642