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J. Selvaraj

Publications (8)

Expression of ITG β-1, MMP9 and Vimentin in Oral Squamous Cell Carcinoma – A Real Time PCR Based Approach

Krishnapriya Umashankar, J. Selvaraj & Pratibha Ramani · Journal of Pharmaceutical Research International · 2021

Background: Oral Squamous Cell Carcinoma (OSCC) is the most common malignancies which accounts for 90% of oral cancer worldwide. The 5 year survival rate of OSCC is not more than 60% due to tumor metastasis and subsequent recurrence. Aim: To compare the gene expression of ITG β-1...

Open access Research Article 10.9734/jpri/2021/v33i44B32653

Comparative Evaluation on the Expression of Pi3 Kinase - AKT- mTOR Signalling Molecules in Oral Squamous Cell Carcinoma - A Real Time PCR Based Approach

Krishnapriya Umashankar, J. Selvaraj & Pratibha Ramani · Journal of Pharmaceutical Research International · 2021

Background: Oral squamous cell cancer (OSCC) develops as a result of the accumulation of many genetic mutations that are influenced by genetic predisposition. Upon acquisition of genetic predisposition, the precancerous cells will transform into malignant cells culminating into c...

Open access Research Article 10.9734/jpri/2021/v33i44A32605

In vitro Anti-inflammatory Properties in Various Extracts (Ethanol, Chloroform and Aqueous) of Kaempferia galanga Linn Rhizome

Hooriyah Laiq Ahmed Khan, G. Sridevi, J. Selvaraj & S. Preetha · Journal of Pharmaceutical Research International · 2021

Introduction: Kaempferia galanga is a medicinal plant belonging to the family Zingiberaceae: ginger family. It is treated as a folk traditional herb. Anti Inflammatory property refers to the ability of a substance to reduce inflammation or any of its 5 cardinal signs. Aim: To ass...

Open access Research Article 10.9734/jpri/2021/v33i47B33146

Regulation of Chloride Intracellular Channel Protein 1 and Caspase -3 mRNA Expression by Hydroethanolic Extract of Aegle marmelos Fruit Human Breast Cancer Cell Line-MCF-7

S. Dhivya, R. Gayatri Devi, J. Selvaraj & A. Jothi Priya · Journal of Pharmaceutical Research International · 2021

Introduction: Cancer is the second leading cause of death all over the world where among all types of cancer breast cancer is said to be the leading cancer followed by lung cancer. The aim of this study is to find the regulation of chloride intracellular channel protein 1 and cas...

Open access Research Article 10.9734/jpri/2021/v33i47B33158

Effect of Aegle Marmelos Hydroethanolic Leaf Extract on Expression of Antiapoptotic Markers in Human Melanoma Cells

S. Bhavesh, G. Sridevi, J. Selvaraj & S. Preetha · Journal of Pharmaceutical Research International · 2021

Background: Aegle marmelos commonly known as Bael is a herbal plant. Itis from a family called Rutaceae. It has many medicinal uses: anti-diarrheal, anti- microbial, anti-viral, anti-cancer, chemo-preventive, Ulcer healing and many others. Aim: To study the effect of Aegle marmel...

Open access Research Article 10.9734/jpri/2021/v33i47B33159

Effect of Kabasura Kudineer Extract on Inflammatory Cytokines [Interleukin-6 and Tumour Necrosis Factor-α] in Lung Cancer Cell Line A549

M. Afrin Nisha, S. Preetha, J. Selvaraj & G. Sridevi · Journal of Pharmaceutical Research International · 2021

Background: Kabasura kudineer is widely known for its anticancer efficiency. Kabasura kudineer is a customary formulation used by siddha practitioners for effectively managing common respiratory illness. Herbal medicines are acknowledged as a great approach to lung cancer therapy...

Open access Research Article 10.9734/jpri/2021/v33i47B33167

Correlation of the Protein Expression of Salivary Cortisol, Serum Vitamin B12 and Interleukin 1 Beta in Patients with Recurrent Aphthous Stomatitis

R. Deepa Viswasini, Pratibha Ramani & J. Selvaraj · Journal of Pharmaceutical Research International · 2021

This study will help in determining which molecules participate in the ulceration with an integrated approach combining external and internal factors. Recurrent aphthous stomatitis (RAS) is a common condition affecting the oral mucosa. Clinically it is manifested through recurren...

Open access Research Article 10.9734/jpri/2021/v33i47A33003

Combination Assay for Tumor Markers in Saliva of Potentially Malignant Disorders and Oral Squamous Cell Carcinoma

Jembulingam Sabarathinam, Sreedevi Dharman & J. Selvaraj · Journal of Pharmaceutical Research International · 2020

Potentially malignant disorders are “the risk of malignancy being present in a lesion or condition either at the time of initial diagnosis or at a future date” include mainly leukoplakia, erythroplakia, oral lichen planus, oral submucous fibrosis. Biomarkers were of immense help...

Open access Research Article 10.9734/jpri/2020/v32i1830687