Jacob Adewale Siyanbade

Neuro-modulatory Potency of Sinapic Acid in Tramadol Hydrochloride Excessive Exposure Induced Anxiety-like Behavior, Neuro-Inflammatory Cytokine, Oxidative and Morphological Damage in the Pre-frontal Cortex in Rats’ Model

Sunday Aderemi Adelakun, Jacob Adewale Siyanbade, Kehinde Precious Adelusi, Opeyemi Zainab Kaka & Luke Gbenga Ogungbe · International Neuropsychiatric Disease Journal · 2025

Tramadol hydrochloride (TRM) is widely used for pain management, but chronic exposure can lead to neurotoxicity. Sinapic acid (SA) has been reported to be a potent antioxidant. This study investigates the impacts of SA against TRM-induced oxidative and morphological damage in the...

Open access Research Article 10.9734/indj/2025/v22i2474

Efficacy of Zinc Sulphate on Fertility Detrimental Effects of Methanol Extract of Sphenocentrum Jollyanum Root in Male Wistar Rats

Ebenezer Adeola ASHAMU, Taiwo Oluseyi Adebayo, Jacob Adewale Siyanbade, Olabisi Muinat ADEKUNLE, Isaac Oluwatobi Olaniyan & Adeniyi Noah OLALERE · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2025

Sphenocentrum jollyanum has many traditional uses across West Africa but its adverse effects on male fertility have been reported and this posed the need for an adjuvant. Zinc is known for improving sperm health but its impact has not been studied against the effects of Sphenocen...

Open access Research Article 10.9734/ajrimps/2025/v14i2309