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Jainey P. James

Publications (3)

Virtual Screening, Molecular Docking and Pharmacophore Modeling of Phytoconstituents of Flavones as Aldose Reductase Inhibitors

Jainey P. James, Asmath Maziyuna Fabin, Pradija Sasidharan & Pankaj Kumar · Journal of Pharmaceutical Research International · 2021

Flavones are an important class of naturally occurring heterocycles possessing various pharmacological activities. An in silico approach was carried out where 506 compounds containing flavone ring were utilised as ligand against the target aldose reductase enzyme. Aldose reductas...

Open access Research Article 10.9734/jpri/2021/v33i41B32348

Design and Identification of Lead Compounds Targeting Nipah G Attachment Glycoprotein by In Silico Approaches

Jainey P. James, . Apoorva, Shreya Renita Monteiro, K. B. Sukesh & A. Varun · Journal of Pharmaceutical Research International · 2021

Nipah virus (NiV) caused several outbreaks in Asian countries, including the latest one from the Kerala state of India. There is no drug available against NiV till now, despite its urgent requirement. There are reports about the anti-influenza viral drug Favipiravir, which has po...

Open access Research Article 10.9734/jpri/2021/v33i40A32232

Synthesis and Antimicrobial Activity of Some New Coumarin Incorporated Pyridine-3-carbonitrile Derivatives

Abhishek Kumar, Pankaj Kumar, Prashant Nayak, D. S. Sandeep, Sneh Priya, Jainey P. James & H. Shravya · Journal of Pharmaceutical Research International · 2021

Drug resistance causes serious difficulties in the routine therapy for curing common microbial infections. Thus it is very essential to develop new antimicrobial agents which can offer alternative treatments. The development of potent and effective antimicrobial agents is of utmo...

Open access Research Article 10.9734/jpri/2021/v33i21A31364