Jonathan Lindsey

Design, Synthesis, and Utility of Defined Molecular Scaffolds

Daisuke Sato, Zhiyuan Wu, Hikaru Fujita & Jonathan Lindsey · Organics · 2021

A growing theme in chemistry is the joining of multiple organic molecular building blocks to create functional molecules. Diverse derivatizable structures—here termed “scaffolds” comprised of “hubs”—provide the foundation for systematic covalent organization of a rich variety of...

Open access Research Article 10.3390/org2030013

Dihydrooxazine Byproduct of a McMurry–Melton Reaction en Route to a Synthetic Bacteriochlorin

Vy-Phuong Tran, Nobuyuki Matsumoto, Phattananawee Nalaoh, Haoyu Jing, Chih-Yuan Chen & Jonathan Lindsey · Organics · 2022

A synthetic route to gem-dimethyl-substituted bacteriochlorins—models of native bacteriochlorophylls—relies on the formation of a dihydrodipyrrin precursor via a series of established reactions: van Leusen pyrrole formation, Vilsmeier formylation, Henry reaction, borohydride redu...

Open access Research Article 10.3390/org3030019