Mechanochemical Synthesis, Spectroscopic Characterization and Molecular Structure of Piperidine–Phenytoin Salt
María Isabel Amil-Miranda, Armando Pineda-Contreras, Francisco Javier Martínez-Martínez, Marcos Flores-Álamo, Hector García-Ortega & Juan Saulo González-González · Organics · 2025
Phenytoin is an anticonvulsant drug that suffers from low aqueous solubility. The formation of phenytoin salts is a strategy employed to address this issue. A phenytoin–piperidine salt (PPD–PNT) was synthesized by solvent-assisted grinding and characterized by infrared (IR) spect...
Open access
Research Article
10.3390/org6030038