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Jude Efiom Okokon

Publications (8)

Effect of Telfairia occidentalis Stem Extract and Fractions on Parasitaemia, Oxidative Stress Markers, Lipid Profile, Hematological Parameters, Liver Function Indices and Liver Histology in Plasmodium berghei Infected Mice

Jude Efiom Okokon, Chinyelu C. Osigwe, Ukeme Essien Andrew, Uwaeme Ugonma Florence, John A Udobang & Uduak P. Ise · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

Telfairia occidentalis Hook (Cucurbitaceae family) is a pumpkin widely used for dietary purposes and in traditional healthcare by Ibibios of Nigeria, as remedy for   various diseases such as malaria, diabetes, pains among others. Telfairia occidentalis stem extract and fractions...

Open access Research Article 10.9734/ajbgmb/2025/v17i1436

In vivo Alpha Amylase and Alpha Glucosidase Inhibitory Activities of Hippocratea africana Root Extract and Fractions

Jude Efiom Okokon, John A. Udobang, Chinyere P. Chidiebere & Augustine I. Bassey · South Asian Journal of Parasitology · 2021

Aim: To study the in vivo alpha amylase and alpha glucosidase inhibitory activities of Hippocratea africana root extract and fractions. Methods: The root extract (200, 400, 600 mg/kg) and fractions (n-hexane, dichloromethane, ethyl acetate and methanol, 400 mg/kg) of H. africana...

Open access Research Article

Subacute Toxicity Study of Stem Extract of Telfairia occidentalis in Rats

Ukeme Essien Andrew, Jude Efiom Okokon, Chinyelu Clementina Osigwe, Ugonma Florence Uwaeme & Uduak Peter Isenigeri · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

Telfairia occidentalis Hook (Cucurbitaceae) is used in Ibibio ethnomedicine for the treatment of diverse diseases such as malaria, diabetes and gastrointestinal disorders.  Evaluation of subacute administration of ethanol stem extract of Telfaira occidentalis for effect on hemato...

Open access Research Article 10.9734/ajbgmb/2025/v17i2440

Inhibitory Potential of Tetrapleura tetraptera Fruit Extract on Alpha Amylase and Alpha Glucosidase Activities in Rats

Chinyelu Clementina Osigwe, Ugonma Florence Uwaeme, Jude Efiom Okokon & Utibe Anietie Edem · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

Diabetes mellitus is a metabolic disorder posing a serious global health concern, necessitating the need for investigation for alternative management and treatment strategies including phytomedicine. Tetrapleura tetraptera (Taub) (family Fabaceae, a medicinal plant used locally i...

Open access Research Article 10.9734/ajbgmb/2025/v17i7476

Antiulcer Activity of Justicia insularis Leaf Extract on Experimentally-Induced Ulcers in Rats

Ugonma Florence Uwaeme, Chinyelu Clementina Osigwe & Jude Efiom Okokon · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

Peptic ulcer disease (PUD) is a significant gastrointestinal disorder that affects millions of people worldwide, imposing substantial burden on individuals, healthcare systems and economies. The available treatment options are not devoid of attendant sequalae. The search for less...

Open access Research Article 10.9734/ajbgmb/2025/v17i4457

Chemical Composition, Genotoxic and Cytotoxic Activities of Methanol Fruit Extract of African Spice Tetrapleura tetraptera

Godwin Ndarake Enin, Itoro Joseph Archibong, Goodluck Mark Wisdom, Basil Nse Ita & Jude Efiom Okokon · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

Tetrapleura tetraptera is a medicinal plant commonly found in most West Africa communities with a widespread medicinal use such as inflammation, convulsions, leprosy, asthma, hypertension, schistosomiasis, and malaria. It is also known for its antimicrobial, neuromuscular, and an...

Open access Research Article 10.9734/ajbgmb/2025/v17i7474

Evaluation of Genotoxic and Cytotoxic Activities of Three Vegetables (Heinsia crinata, Justicia insularis and Lasianthera africana) Using Allium cepa Test

Emmanuella Chinyere Ikechukwu, Peace Nwachukwu Agu, Hephzibah Boluwatito Olumuji, Martin Osita Anagboso, Imoh Imeh Johnny, Jude Efiom Okokon & Nwakaego Omonigho Ebong · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2024

Heinsia crinata (Afzel.) G. Taylor (Rubiaceae), Justicia insularis T.  Anderson (Acanthaceae family) and Lasianthera africana. P.Beav (Stemonuraceae), which are used as vegetables in the preparation of soups and as medicine traditionally to treat various diseases by the Ibibios w...

Open access Research Article 10.9734/ajbgmb/2024/v16i4367

In vitro Antioxidant and Biological Activities of Extract and Fractions from Telfairia occidentalis Stems

Godwin Ndarake Enin, Basil Nse Ita, Blessing Jumbo, Mfoniso Udofot James, Sarah Etim Joseph, Bassey Sunday Antia, Paul Sunday Thomas & Jude Efiom Okokon · South Asian Research Journal of Natural Products · 2024

Telfairia occidentalis (TO) Hook is a widely consumed vegetable in Nigeria. This study investigated the antioxidant and antidiabetic activities of stem ethanol extract (ETTO) and fractions (hexane, HTO; dichloromethane, DTO; ethylacetate, ETO; methanol, MTO and aqueous, Aq.TO) fr...

Open access Research Article