Purpose: To update the accommodation mechanisms and propose a dual-wavelength, dual-function laser system for presbyopia and glaucoma treatments. Study Design: Laser sclera softening (LSS) for increased accommodation of presbyopic eyes. Place and Duration of Study: New Taipei Cit...
Open access
Research Article10.9734/or/2023/v18i1378
Purpose: To derive and provide analytic formulas and proposed protocol for accommodative gain of presbyopia eyes via laser scleral softening, which causes increased space between ciliary body and lens (SCL) and mobility of the posterior vitreal zonules (PVZ). Study Design: To inc...
Open access
Research Article10.9734/or/2022/v16i430243
Purpose: To derive and provide, for the first time, comprehensive analytic formulas for scleral softening volume efficacy (SVE) for accommodative gain (AG) via the increased space between ciliary body and lens (SCL) and mobility of the posterior vitreous zonules (PVZ). Study Desi...
Open access
Research Article10.9734/or/2022/v16i430244
Purpose: To analyze the safety and efficacy of corneal photovitrification (CPV) for improved visions of age-related macular degeneration (AMD) eyes. Study Design: Using CPV for improved visions of AMD eyes. Place and Duration of Study: New Taipei City, Taiwan, and Austin, TX, USA...
Open access
Research Article10.9734/or/2022/v16i330238
Purpose: To analyze the factors influencing the corneal crosslinking (CXL) efficacy and comparison of epi-on and epi-off procedures. Study Design: modeling the efficacy of epi-off and epi-on CXL. Place and Duration of Study: New Taipei City, Taiwan, between November, 2021 and Dec...
Open access
Research Article10.9734/or/2021/v15i430221
Purpose: To explore (theoretically) the key parameters and their influence on the time profiles of photosensitizer (riboflavin), free radicals, singlet oxygen, oxygen and the efficacy of corneal collagen crosslinking (CXL) in both type-I and oxygen-mediated type-II mechanisms, sp...
Open access
Research Article10.9734/or/2021/v15i430217
Aims: To resolve the controversial issues of UV-light-initiated corneal collagen cross-linking (CXL) by theoretical formulas and measured clinical outcomes. Study Design: Analysis and measured data of CXL. Place and Duration of Study: New Vision Inc, Taipei, between June 2021 an...
Open access
Research Article10.9734/or/2021/v15i130204
Purpose: To derive and provide analytic formulas for an accommodative gain of presbyopia eyes. via sclera ablation and/or thermal shrinkage such that the lens is reshaped and/or its position is shifted. New mechanisms are also proposed. Study Design: To increase the accommodation...
Open access
Research Article10.9734/or/2021/v15i130203
Purpose: To update and review the technology and principles of laser presbyopia reversal (LAPR) via sclera ablation and thermal shrinkage using infrared and UV lasers. Recent clinical data and new methods are also summarized. Study Design: LAPR using laser sclera ablation for inc...
Open access
Research Article10.9734/or/2021/v14i430199
Aims: To derive kinetic equations and analytic formulas for efficacy enhancement of corneal collagen crosslinking (CXL) in a 2-initiator system. Study Design: Modeling the kinetics of CXL. Place and Duration of Study: Taipei, Taiwan, between between January 2019 to June, 2019. M...
Open access
Research Article10.9734/or/2019/v10i330109
Aims: To derive analytic formulas for the overall efficacy of corneal collagen crosslinking (CXL) based on coupled kinetic equations including both non-oxygen-mediated (NOM) and oxygen-mediated (OM) type-II mechanisms. Study Design: modeling the kinetics of CXL. Place and Durati...
Aims: To derive analytic formulas for the efficacy of type-II corneal collagen crosslinking (CXL) based on coupled macroscopic kinetic equations with an emphasis on the role of oxygen. Study Design: modeling and analysis of type-II CXL Place and Duration of Study: Taipei, Taiwan,...
Aims: To derive formulae and analyze the roles of ocular components of human eye on the refractive power in various applications. Study Design: Gaussian optics analysis. Place and Duration of Study: Taipei, Taiwan, between May 2015 and August 2016. Methodology: An effective eye m...
Aims: To analyze the combined factors for safety and optimal efficacy for UV-light-initiated corneal collagen cross-linking (CXL). Study Design: Modeling and analysis of CXL. Place and Duration of Study: New Vision Inc, Taipei, between Oct. 2015 and July 2016. Methodology: Analyt...
Purpose: To update and derive formulas for the efficacy and kinetics of corneal collagen crosslinking (CXL) including both type-I and oxygen-mediated type-II mechanisms, the role of oxygen, the initiator regeneration, safety dose, minimum corneal thickness and demarcation line de...
Open access
Research Article10.9734/or/2021/v14i430200