K. Vanitha Sree

Galangin and Piperine Attenuate Bleomycin-Induced Pulmonary Fibrosis by Modulating Oxidative Stress and MPO-Mediated Inflammation

K. Vanitha Sree, M. USHA RANI, A. GOPALA REDDY, B. RAJENDER, D. DURGA VEERA HANUMAN, K V Venkata Rao & Bhaskar Debberma · Journal of Advances in Biology & Biotechnology · 2025

Aims: To evaluate and compare the protective efficacy of galangin and piperine—individually and in combination—against bleomycin-induced pulmonary fibrosis in C57BL/6 mice, with emphasis on oxidative and nitrosative stress modulation and histopathological recovery. The study focu...

Open access Research Article 10.9734/jabb/2025/v28i113328

Targeting TGF-β1/MMP-9/α-SMA Signaling Axes Using Piperine and Galangin in Bleomycin Induced Pulmonary Fibrosis Model

K. Vanitha Sree, M. USHA RANI, A. GOPALA REDDY, M. LAKSHMAN, B. RAJENDER, D. DURGA VEERA HANUMAN, K V Venkata Rao & DIPALI P. PATIL · Journal of Advances in Biology & Biotechnology · 2025

Aims: To evaluate and compare the anti-fibrotic efficacy of galangin and piperine alone and in combination against bleomycin-induced pulmonary fibrosis in C57BL/6 mice, using biochemical (hydroxyproline, TGF-β1), histological (Masson’s trichrome), and immunohistochemical (MMP-9,...

Open access Research Article 10.9734/jabb/2025/v28i113274

Hepatoprotective Effects of Piperine on Thioacetamide-Induced Hepatotoxicity in Rats: A Lipid Profile Analysis

Bhaskar Debbarma, M Usha Rani, P. Shivakumar, D. Madhuri, K. SATISH KUMAR, D D V Hanuman, K. Vanitha Sree & Ramavtar · Journal of Advances in Biology & Biotechnology · 2024

Piperine is an alkaloid primarily found in the fruits of Piper nigrum L. (black pepper) and Piper longum L. (long pepper), which belong to the Piperaceae family. It is also present in smaller amounts in the roots of these plants. They possesses bio-enhancing properties, has a lon...

Open access Research Article 10.9734/jabb/2024/v27i91401