Kabir Abdu

Nucleophilic Groups Protection of Phosphoramidite for DNA Synthesis

Kabir Abdu · International Research Journal of Pure and Applied Chemistry · 2016

Phosphoramidite are the DNA building blocks. For the DNA synthesis to proceed it is necessary to block or protect all the nucleophilic centres not involved in the reaction at each step of the synthesis. The commonly used DNA protecting groups includes; dimethoxytrityl (DMT) which...

Open access Research Article 10.9734/IRJPAC/2016/30132

Fluorescence Binding Assay of Atl1 Protein with the SIMA Labelled Oligonucleotide Containing the Tricyclic Nucleoside Analogue of O6-methyl-2'-deoxyguanosine

Kabir Abdu & David M. Williams · Chemical Science International Journal · 2015

The synthesis of phosphoramidite (DNA building block) containing the tricyclic nucleoside analogue of O6-methyl-2-deoxyguanosine was carried out and its Interactions with Atl proteins was quantified through fluorescent assay (fluorescent intensity monitoring). In fluorescent assa...

Open access Research Article 10.9734/ACSJ/2015/17369