Methotrexate-associated Demyelinating Leukoencephalopathy after Low-dose Oral Therapy in a Patient with Post-viral Polyarthralgia
Singireddy Dattakshaya, Kollipara Lakshmi Srivalli, Kattepogu Hansitha, Devara Gowri Priya, Banavath Durga Bhavani & Tata Leela Ram Gopal · Asian Journal of Medical Principles and Clinical Practice · 2026
Background: Methotrexate is a widely used disease-modifying antirheumatic drug. Neurological toxicity is uncommon, particularly after short-term, low-dose oral treatment, and may resemble acute cerebrovascular disease. Case Presentation: A 44-year-old woman receiving oral methotr...