Prediction of the Inhibitory Concentration of Hydroxamic Acids by DFT-QSAR Models on Histone Deacetylase 1
Doh Soro, Lynda Ekou, Mamadou Guy-Richard Koné, Tchirioua Ekou, Sopi Thomas Affi, Lamoussa Ouattara & Nahossé Ziao · International Research Journal of Pure and Applied Chemistry · 2018
In order to study the relationship between inhibitory concentration and the molecular structures of hydroxamic acids, a Quantitative Structure Activity Relationship (QSAR) study is applied to a set of 31 histone deacetylase inhibitors (HDACi). This study is performed by using the...
Open access
Research Article
10.9734/IRJPAC/2018/40895