M. G. C. Mayeiro

Two Faces of Regulatory T Cells: From Immune Defense to Tumoral Progression

S. S. D. E. Medeiros, L. G. De Souza, W. M. Souza, M. G. C. Mayeiro & G. R. Degasperi · Annual Research & Review in Biology · 2020

T cells are the most important cellular element of human immunity defending against virus, bacteria, non-self-tissue and tumor cells. Regulatory T cells (Tregs) are the major responsible for self-tolerance maintenance, especially those expressing forkhead box protein 3 (FOXP3) tr...