Chemo- and Regioselective 1,3-Dipolar Cycloaddition of Nitrile Imines to 5-Arylmethylene-2-methylthiohydantoins
Maria E. Filkina, Lev A. Lintsov, Victor A. Tafeenko, Maxim E. Kukushkin & Elena K. Beloglazkina · Organics · 2026
1,3-Dipolar cycloaddition reactions of nitrile imines are a powerful tool for the construction of spirocyclic frameworks, yet controlling chemoselectivity remains challenging when dipolarophiles contain multiple reactive sites. In this study, we investigated the cycloaddition of...
Open access
Research Article
10.3390/org7010007