Application of Substituent Electronic Descriptors QSAR Model of 2-amino-6-arylsulfonylbenzonitriles as HIV-1 Reverse Transcriptase Inhibitors based on the MOLMAP Approach
Razieh Sabet & Maryam Sabet · Asian Journal of Applied Chemistry Research · 2018
The HIV-1 reverse transcriptase (RT) is a major target for drug development. Inhibition of this enzyme has been one of the primary therapeutic strategies in suppressing the replication of HIV-1. A series of 2-amino-6-arylsulfonylbenzonitrile derivatives were subjected to quantita...
Open access
Research Article
10.9734/ajacr/2018/v1i29617