Mayowa Josiah Badmus

Why Cancer Immunotherapy Fails?: Mechanisms of Resistance and Emerging Reversal Strategies

Muhydeen Damilola Badru, Tobi Ayomide Lawal, Udeichi Nnenna Chidimma, Mayowa Josiah Badmus, Francis Esther Ene, Daniel Chinaza Anyirionye, Naomi Ngozichukwuka Ajoniloju, Adegbesan Abiodun Christopher & Comfort Mary Afolabi · Journal of Cancer and Tumor International · 2025

Cancer immunotherapy has revolutionized the field of oncology by enabling the immune system to target and destroy cancer cells. Therapies such as immune checkpoint inhibitors, including PD-1/PD-L1 and CTLA-4 blockade, and chimeric antigen receptor T (CAR-T) cells have shown unpre...

Open access Research Article 10.9734/jcti/2025/v15i3306

BRCA Mutations in Breast Cancer Insights into Genetic Risk and Tailored Therapeutic Interventions

Lawrence John AJutor, Edibokun Theresa Orobator, Blessing Ben- Anioke, Victor Chiedozie Ezeamii, Mayowa Josiah Badmus, Uchechi Ngozichukwu Obiefule, Vincent Barrah, Mary Oluwabunmi Oyebode & Josiah Stephen · Journal of Cancer and Tumor International · 2025

BRCA1 and BRCA2 genes, located on separate chromosomes, encode crucial multifunctional proteins that are important for correcting errors in DNA replication and cell division. The two genes work in tandem at different stages in the DNA damage response and for DNA repair and could...

Open access Research Article 10.9734/jcti/2025/v15i2296